Third Annual Chapel Hill Drug Conference: Academic Drug Discovery
May 16–17, 2008
The Paul T. Rizzo Conference Center
UNC-Chapel Hill,
Chapel Hill, North Carolina
Sponsored by
Each spring the School of Pharmacy at UNC-Chapel Hill hosts a conference covering an emerging and exciting aspect of drug discovery. This spring’s conference focuses on academic drug discovery. Scientists from all disciplines engaged in biomedical research who are interested in a better understanding of the drug discovery process and future prospects for academic contribution to new medicines will benefit from participation in this conference. It features a stimulating series of talks that cover the spectrum from successfully launched medicines discovered in academia and novel chemical biological approaches for target and lead identification to organizing concepts and challenges for academic centers for drug discovery. An explicit expectation of the meeting is the exchange of best practice and emerging approaches to the scientific, organizational, and business development challenges facing academic drug discovery centers.
The conference has reached full capacity; registration is closed.
Support
Conference organizers gratefully acknowledge support from:
Program
Friday, May 16
| Continental breakfast |
| Session 1: Case Histories of Drugs Discovered in Academia |
| Lunch |
| Session 2: Chemical Biology, Target and Lead Identification |
| Symposium Dinner at the DuBose House |
Saturday, May 17
| Continental breakfast |
| Session 3: Academic Drug Discovery Centers: Progress, Challenges, and Emerging Results |
| Box lunch |
Topics and Speakers
“Serendipity vs. Rationale in Drug Discovery from Academic Research: An Illustration”
Harel Weinstein, Maxwell M. Upson Professor of Physiology and Biophysics; Chairman, Department of Physiology and Biophysics; Director, Institute for Computational Biomedicine, Weill Medical College of Cornell University
with Ming-Ming Zhou, Professor and Chairman, Department of Structural and Chemical Biology, Mount Sinai School of Medicine, Icahn Medical Institute
“Restoring Protein Homeostasis to Ameliorate Diseases of Complex Etiology”
Jeff Kelly, Dean of Graduate and Postgraduate Studies, Lita Annenberg Hazen Professor of Chemistry, Skaggs Institute for Chemical Biology, Department of Chemistry, Scripps Research Institute
“New Therapies For Treating Cancer, Inflammation and Viral Diseases”
Dennis Liotta, Professor of Chemistry and Director of the Emory University Molecular Library Screening Center, Emory University
“The NIH Chemical Genomics Center: Bringing Biopharmaceutical Technologies to Academic Drug Discovery”
Chris Austin, Director of the NIH Chemical Genomics Center, National Institutes of Health
“Discovery and Development of Antimalarials”
Kip Guy, Chair, Chemical Biology and Therapeutics, St. Jude Children’s Hospital
“Drug Design from Enzymatic Transition State Theory”
Vern Schramm, Professor and Ruth Merns Chair in Biochemistry, Albert Einstein College of Medicine
“Parallel and Phenotypic Screening Rapidly Yields Therapeutic Lead-like Compounds”
Bryan Roth, Distinguished Professor of Pharmacology, School of Medicine and Professor, Division of Medicinal Chemistry and Natural Products, School of Pharmacy, UNC-Chapel Hill
“Receptor Functional Selectivity and Drug Discovery: Opportunity or Obfuscation”
Richard Mailman, Professor of Psychiatry, Pharmacology, Neurology, and Medicinal Chemistry, UNC-Chapel Hill
“Generating Freely-available Chemical Probes for Human Proteins”
Al Edwards, Professor of Chemistry and Director and CEO of the Structural Genomics Consortium, Banting and Best Department of Medical Chemistry, University of Toronto
“Inhibitors of the Soluble Epoxide Hydrolase to Treat Hypertension and Inflammation”
Bruce Hammock, Distinguished Professor of Entomology and Cancer Research Center Director, NIEHS-UCD Superfund Basic Research Program, PI NIH Biotechnology Training Program, University of California, Davis
“Chemical Biology of Orphan Nuclear Receptors: Lessons for Protein Family-based Drug Discovery”
Tim Willson, Department Head of Exploratory Chemistry, Molecular Discovery Research, GlaxoSmithKline, Research Triangle Park, NC, and Stevenage, UK
“Public-Private Partnerships at NIH”
Barbara Mittleman, Director, Public-Private Partnership Programs, NIH Office of the Director, Office of Science Policy Analysis
Why Academic Drug Discovery?
Scientific progress in the biomedical sciences has accelerated enormously over the last two to three decades … click to read more.
See “Why Academic Drug Discovery Makes Sense” in Science Magazine, and visit the UNC Center for Integrative Chemical Biology and Drug Discovery.
Registration
Registration is closed.
The registration fee covers all conference materials and meals—breakfast, lunch, and dinner* on the 16th; breakfast and box lunch on the 17th.
Lodging
A block of rooms have been reserved at the Rizzo Center. The cost is $200 per night. Please contact the hotel directly at 919-913-2098 to make your reservation. Other hotels near the Rizzo Center are the Marriott Courtyard Chapel Hill, the Hampton Inn and Suites, and the Holiday Inn Express. There are no rooms reserved at these hotels so please call to make your own reservations.
For More Information
About registration:
Darline Millett
Professional Development and Enrichment Programs
The Friday Center
800-845-8640 or 919-962-2643
e-mail dmillett@email.unc.edu